Do you know molecular hydrogen therapy for post covid-19 recovery of restore immunity?

Hydrogen has been shown to have antioxidant, anti-inflammatory, hormone-regulating, and apoptosis-resistance properties, among others. Based on a review of the research, the use of hydrogen might reduce the destructive cytokine storm and lung injury caused by SARS-CoV-2 during COVID-19 (Corona Virus Disease 2019) in the early stage, stimulating ropy sputum drainage, and ultimately reducing the incidence of severe disease. Molecular hydrogen treatment has the potential to become a new adjuvant therapy for COVID-19, but its efficacy and safety require large clinical trials and further confirmation.

Hydrogen and Oxidative Stress Reactions in COVID-19

Superoxide dismutase (SOD) is an important antioxidant enzyme in the antioxidant defense system of the body. It can remove a variety of toxic or oxidizing substances in the body to eliminate the damage to DNA and biological functional proteins caused by these substances to maintain the stability of the internal environment and contribute to anti-toxicity and anti-oxidation processes (Gwarzo and Muhammad, 2010). After hydrogen treatment, the content of malondialdehyde in lung tissue can be reduced, increasing the activity of SOD (Shi et al. 2013). This helps to maintain the stability of the internal environment of the body to achieve excessive activation of oxidative processes and reduce the oxidative stress caused by the ROS pathway. Multiple organ failure is a common cause of death in critically ill COVID-19 patients. Hydrogen may be used to protect multiple organs including the heart, kidney, and nervous system via anti-apoptotic and anti-oxidative functions to maintain the normal response of the body and reduce mortality (Hayashida et al., 2012Hayashida et al., 2014Homma et al., 2014).

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